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Faculty of Engineering Science

Chair of Cellular Biomechanics - Prof. Dr. Dr. Elisabetta Ada Cavalcanti-Adam

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Publications

2024

Waseem Kitana, Victoria Levario Diaz, Elisabetta Ada Cavalcanti-Adam, Leonid Ionov: Biofabrication of Composite Bioink-Nanofiber Constructs : Effect of Rheological Properties of Bioinks on 3D (Bio)Printing and Cells Interaction with Aligned Touch Spun Nanofibers. In: Advanced Healthcare Materials, 13 (2024). - .
doi:10.1002/adhm.202303343

2023

Andreas Fink, Charlotte R. Doll, Ana Yagüe Relimpio, Yannik Dreher, Joachim P. Spatz, Kerstin Göpfrich, Elisabetta Ada Cavalcanti-Adam: Extracellular Cues Govern Shape and Cytoskeletal Organization in Giant Unilamellar Lipid Vesicles. In: ACS Synthetic Biology, 12 (2023). - S. 369-374.
doi:10.1021/acssynbio.2c00516

Urszula Hohmann, Julian Cardinal von Widdern, Chalid Ghadban, Maria Cristina Lo Giudice, Grégoire Lemahieu, Elisabetta Ada Cavalcanti-Adam, Faramarz Dehghani, Tim Hohmann: Jamming Transitions in Astrocytes and Glioblastoma Are Induced by Cell Density and Tension. In: Cells, 12 (2023). - .
doi:10.3390/cells12010029

2022

Lluís Oliver‐Cervelló, Helena Martin‐Gómez, Nandin Mandakhbayar, Young‐Woo Jo, Elisabetta Ada Cavalcanti-Adam, Hae‐Won Kim, Maria‐Pau Ginebra, Jung‐Hwan Lee, Carlos Mas‐Moruno: Mimicking Bone Extracellular Matrix : From BMP‐2‐Derived Sequences to Osteogenic‐Multifunctional Coatings. In: Advanced Healthcare Materials, 11 (2022). - .
doi:10.1002/adhm.202201339

Oskar Staufer, Kapil Gupta, Jochen Estebano Hernandez Bücher, Fabian Kohler, Christian Sigl, Gunjita Singh, Kate Vasileiou, Ana Yagüe Relimpio, Meline Macher, Sebastian Fabritz, Hendrik Dietz, Elisabetta Ada Cavalcanti-Adam, Christiane Schaffitzel, Alessia Ruggieri, Ilia Platzman, Imre Berger, Joachim P. Spatz: Synthetic virions reveal fatty acid-coupled adaptive immunogenicity of SARS-CoV-2 spike glycoprotein. In: Nature Communications, 13 (2022). - .
doi:10.1038/s41467-022-28446-x

Andreas Schoenit, Cristina Lo Giudice, Nina Hahnen, Dirk Ollech, Kevin Jahnke, Kerstin Göpfrich, Elisabetta Ada Cavalcanti-Adam: Tuning Epithelial Cell–Cell Adhesion and Collective Dynamics with Functional DNA-E-Cadherin Hybrid Linkers. In: Nano Letters, 22 (2022). - S. 302-310.
doi:10.1021/acs.nanolett.1c03780

Victoria Levario Diaz, Rebecca Elizabeth Alvarado, Cristina Marcela Rodriguez-Quinteros, Andreas Fink, Joel Christian, Wenqian Feng, Elisabetta Ada Cavalcanti-Adam: 1D micro-nanopatterned integrin ligand surfaces for directed cell movement. In: Frontiers in Cell and Developmental Biology, 10 (2022). - .
doi:10.3389/fcell.2022.972624

Kevin Jahnke, Stefan J. Maurer, Cornelia Weber, Jochen Estebano Hernandez Bücher, Andreas Schoenit, Elisa D'Este, Elisabetta Ada Cavalcanti-Adam, Kerstin Göpfrich: Actomyosin-Assisted Pulling of Lipid Nanotubes from Lipid Vesicles and Cells. In: Nano Letters, 22 (2022). - S. 1145-1150.
doi:10.1021/acs.nanolett.1c04254

Elisabeth Grimm, Franciscus van der Hoeven, Donato Sardella, Katrin I. Willig, Ulrike Engel, Nisha Veits, Robert Engel, Elisabetta Ada Cavalcanti-Adam, Felix Bestvater, Luca Bordoni, Richard Jennemann, Kai Schönig, Ina Maria Schiessl, Roger Sandhoff: A Clathrin light chain A reporter mouse for in vivo imaging of endocytosis. In: PLoS One, 17 (2022). - .
doi:10.1371/journal.pone.0273660

Joel Christian, Johannes W. Blumberg, Dimitri Probst, Cristina Lo Giudice, Sandra Sindt, Christine Selhuber-Unkel, Ulrich S. Schwarz, Elisabetta Ada Cavalcanti-Adam: Control of Cell Adhesion using Hydrogel Patterning Techniques for Applications in Traction Force Microscopy. In: JoVE, 179 (2022). - .
doi:10.3791/63121

Chiara Zambarda, Carlos Pérez González, Andreas Schoenit, Nisha Veits, Clara Schimmer, Raimund Jung, Dirk Ollech, Joel Christian, Pere Roca-Cusachs, Xavier Trepat, Elisabetta Ada Cavalcanti-Adam: Epithelial cell cluster size affects force distribution in response to EGF-induced collective contractility. In: European Journal of Cell Biology, 101 (2022). - .
doi:10.1016/j.ejcb.2022.151274

Lucia T. Benk, Amelie S. Benk, Rafael B. Lira, Elisabetta Ada Cavalcanti-Adam, Rumiana Dimova, Reinhard Lipowsky, Benjamin Geiger, Joachim P. Spatz: Integrin αIIbβ₃ activation and clustering in minimal synthetic cells. In: Advanced NanoBiomed Research, 2 (2022). - .
doi:10.1002/anbr.202100094

Joel Christian, Elisabetta Ada Cavalcanti-Adam: Micro-and Nanopatterned Substrates for Studies on the Mechanobiology of Cell–Matrix Adhesions. In: Jun Nakanishi, Koichiro Uto (Hrsg.): Material-based Mechanobiology. - Cambridge, UK : Royal Society of Chemistry, 2022. - S. 135-151.
doi:10.1039/9781839165375-00135

2021

Anna Luise Grab, Dirk Hose, Patrick Horn, Elisabetta Ada Cavalcanti-Adam, Anja Seckinger, Martin Müller: BMP‐6 Loaded Polyelectrolyte Complex Nanoparticles Inducing Osteogenic Differentiation and Apoptosis of Malignant Plasma Cells for Local Treatment of Multiple Myeloma. In: Particle & Particle Systems Characterization, 38 (2021). - .
doi:10.1002/ppsc.202000263

L. Vaiani, E. Migliorini, Elisabetta Ada Cavalcanti-Adam, A. E. Uva, M. Fiorentino, M. Gattullo, V. M. Manghisi, A. Boccaccio: Coarse-Grained Elastic Network Modelling : a Fast and Stable Numerical Tool to Characterize Mesenchymal Stem Cells Subjected to AFM Nanoindentation Measurements. In: Materials Science and Engineering: C, 121 (2021). - .
doi:10.1016/j.msec.2020.111860

Man Zhang, Qian Sun, Yiling Liu, Zhiqin Chu, Leixiao Yu, Yong Hou, Heemin Kang, Qiang Wei, Weifeng Zhao, Joachim P. Spatz, Changsheng Zhao, Elisabetta Ada Cavalcanti-Adam: Controllable ligand spacing stimulates cellular mechanotransduction and promotes stem cell osteogenic differentiation on soft hydrogels. In: Biomaterials, 268 (2021). - .
doi:10.1016/j.biomaterials.2020.120543

Lluís Oliver‐Cervelló, Helena Martin‐Gómez, Leslie Reyes, Fatima Noureddine, Elisabetta Ada Cavalcanti-Adam, Maria‐Pau Ginebra, Carlos Mas‐Moruno: An engineered biomimetic peptide regulates cell behavior by synergistic integrin and growth factor signaling. In: Advanced Healthcare Materials, 10 (2021). - .
doi:10.1002/adhm.202001757

Lluís Oliver-Cervelló, Helena Martín-Gómez, Leslie Reyes, Fatima Noureddine, Elisabetta Ada Cavalcanti-Adam, Maria-Pau Ginebra, Carlos Mas-Moruno: An engineered biomimetic peptide regulates cell behavior by synergistic integrin and growth factor signaling. In: Advanced Healthcare Materials, 10 (2021). - .
doi:10.1002/adhm.202001757

Andreas Schoenit, Elisabetta Ada Cavalcanti-Adam, Kerstin Göpfrich: Functionalization of cellular membranes with DNA nanotechnology. In: Trends in Biotechnology, 39 (2021). - S. 1208-1220.
doi:10.1016/j.tibtech.2021.02.002

Elisa Migliorini, Elisabetta Ada Cavalcanti-Adam, Antonio Emmanuele Uva, Michele Fiorentino, Michele Gattullo, Vito Modesto Manghisi, Lorenzo Vaiani, Antonio Boccaccio: Nanoindentation of mesenchymal stem cells using atomic force microscopy : effect of adhesive cell-substrate structures. In: Nanotechnology, 32 (2021). - .
doi:10.1088/1361-6528/abe748

Markus Mukenhirn, Francesco Muraca, Delia Bucher, Edgar Asberger, Elisa Cappio Barazzone, Elisabetta Ada Cavalcanti-Adam, Steeve Boulant: Role of Clathrin Light Chains in Regulating Invadopodia Formation. In: Cells, 10 (2021). - .
doi:10.3390/cells10020451

Hendrik Boog, Rebecca Medda, Elisabetta Ada Cavalcanti-Adam: Single cell center of mass for the analysis of BMP receptor heterodimers distributions. In: Journal of Imaging, 7 (2021). - .
doi:10.3390/jimaging7110219

Francesca Posa, Elisabeth H. Baha-Schwab, Qiang Wei, Adriana Di Benedetto, Stefanie Neubauer, Florian Reichart, Horst Kessler, Joachim P. Spatz, Corinne Albiges-Rizo, Giorgio Mori, Elisabetta Ada Cavalcanti-Adam: Surface Co-presentation of BMP-2 and integrin selective ligands at the nanoscale favors α₅β₁ integrin-mediated adhesion. In: Biomaterials, 267 (2021). - .
doi:10.1016/j.biomaterials.2020.120484

Federica Pennarola, Elisabetta Ada Cavalcanti-Adam: Surface Patterning for the Control of Receptor Clustering and Molecular Forces of Integrin-Mediated Adhesions. In: Miguel Vicente-Manzanares (Hrsg.): The Integrin Interactome : Methods and Protocols. - New York : Springer US, 2021. - S. 183-195.
doi:10.1007/978-1-0716-0962-0_11

2020

Francesca Posa, Adriana Di Benedetto, Giampietro Ravagnan, Elisabetta Ada Cavalcanti-Adam, Lorenzo Lo Muzio, Gianluca Percoco, Giorgio Mori: Bioengineering bone tissue with 3D printed scaffolds in the presence of oligostilbenes. In: Materials, 13 (2020). - .
doi:10.3390/ma13204471

Nicolás Andrés Saffioti, Elisabetta Ada Cavalcanti-Adam, Diego Pallarola: Biosensors for studies on adhesion-mediated cellular responses to their microenvironment. In: Frontiers in Bioengineering and Biotechnology, 8 (2020). - .
doi:10.3389/fbioe.2020.597950

Qiang Wei, Andrew Holle, Jie Li, Francesca Posa, Francesca Biagioni, Ottavio Croci, Amelie S. Benk, Jennifer Young, Fatima Noureddine, Jie Deng, Man Zhang, Gareth J. Inman, Joachim P. Spatz, Stefano Campaner, Elisabetta Ada Cavalcanti-Adam: BMP‐2 signaling and mechanotransduction synergize to drive osteogenic differentiation via YAP/TAZ. In: Advanced Science, 7 (2020). - .
doi:10.1002/advs.201902931

Tina Wiegand, Marta Fratini, Felix Frey, Klaus Yserentant, Yang Liu, Eva Weber, Kornelia Galior, Julia Ohmes, Felix Braun, Dirk-Peter Herten, Steeve Boulant, Ulrich S. Schwarz, Khalid Salaita, Elisabetta Ada Cavalcanti-Adam, Joachim P. Spatz: Forces during cellular uptake of viruses and nanoparticles at the ventral side. In: Nature Communications, 11 (2020). - .
doi:10.1038/s41467-019-13877-w

Julius Sefkow-Werner, Paul Machillot, Adria Sales, Elaine Castro-Ramirez, Melissa Degardin, Didier Boturyn, Elisabetta Ada Cavalcanti-Adam, Corinne Albiges-Rizo, Catherine Picart, Elisa Migliorini: Heparan sulfate co-immobilized with cRGD ligands and BMP2 on biomimetic platforms promotes BMP2-mediated osteogenic differentiation. In: Acta Biomaterialia, 114 (2020). - S. 90-103.
doi:10.1016/j.actbio.2020.07.015

Maurizio Wack, Tina Wiegand, Friedrich Frischknecht, Elisabetta Ada Cavalcanti-Adam: An in vitro DNA Sensor-based Assay to Measure Receptor-specific Adhesion Forces of Eukaryotic Cells and Pathogens. In: Bio-protocol, 10 (2020). - .
doi:10.21769/BioProtoc.3733

Leixiao Yu, Yong Hou, Wenyan Xie, Jose Luis Cuellar Camacho, Chong Cheng, Andrew Holle, Jennifer Young, Britta Trappmann, Weifeng Zhao, Matthias F. Melzig, Elisabetta Ada Cavalcanti-Adam, Changsheng Zhao, Joachim P. Spatz, Qiang Wei, Rainer Haag: Ligand diffusion enables force‐independent cell adhesion via activating α5β1 integrin and initiating rac and RhoA signaling. In: Advanced Materials, 32 (2020). - .
doi:10.1002/adma.202002566

Dirk Ollech, Tim Pflästerer, Adam Shellard, Chiara Zambarda, Joachim Pius Spatz, Philippe Marcq, Roberto Mayor, Richard Wombacher, Elisabetta Ada Cavalcanti-Adam: An optochemical tool for light-induced dissociation of adherens junctions to control mechanical coupling between cells. In: Nature Communications, 11 (2020). - .
doi:10.1038/s41467-020-14390-1

Adriana Di Benedetto, Francesca Posa, Mario Marazzi, Zamira Kalemaj, Roberta Grassi, Lorenzo Lo Muzio, Mariasevera Di Comite, Elisabetta Ada Cavalcanti-Adam, Felice Roberto Grassi, Giorgio Mori: Osteogenic and chondrogenic potential of the supramolecular aggregate T-LysYal®. In: Frontiers in Endocrinology, 11 (2020). - .
doi:10.3389/fendo.2020.00285

Qiang Wei, Jennifer Young, Andrew Holle, Jie Li, Karen Bieback, Gareth Inman, Joachim P. Spatz, Elisabetta Ada Cavalcanti-Adam: Soft hydrogels for balancing cell proliferation and differentiation. In: ACS Biomaterials Science & Engineering, 6 (2020). - S. 4687-4701.
doi:10.1021/acsbiomaterials.0c00854

Elisabetta Ada Cavalcanti-Adam, Wenqian Feng: Surface functionalization of biomaterials for cell biology applications. In: Nihal Engin Vrana, Helena Knopf-Marques, Julien Barthes (Hrsg.): Biomaterials for Organ and Tissue Regeneration : New Technologies and Future Prospects. - Duxford : Woodhead Publishing, 2020. - S. 163-176.
doi:10.1016/B978-0-08-102906-0.00004-0

2019

Christian Hiepen, Jerome Jatzlau, Susanne Hildebrandt, Branka Kampfrath, Melis Goktas, Arunima Murgai, Jose Luis Cuellar Camacho, Rainer Haag, Clemens Ruppert, Gerhard Sengle, Elisabetta Ada Cavalcanti-Adam, Kerstin C. Blank, Petra Knaus: BMPR2 acts as a gatekeeper to protect endothelial cells from increased TGFβ responses and altered cell mechanics. In: PLoS Biology, 17 (2019). - .
doi:10.1371/journal.pbio.3000557

Elisabetta Ada Cavalcanti-Adam: Building nanobridges for cell adhesion. In: Nature Materials, 18 (2019). - S. 1272-1273.
doi:10.1038/s41563-019-0537-7

Francesca Posa, Anna Luise Grab, Volker Martin, Dirk Hose, Anja Seckinger, Giorgio Mori, Slobodan Vukicevic, Elisabetta Ada Cavalcanti-Adam: Copresentation of BMP-6 and RGD ligands enhances cell adhesion and BMP-mediated signaling. In: Cells, 8 (2019). - .
doi:10.3390/cells8121646

Anna Luise Grab, Anja Seckinger, Patrick Horn, Dirk Hose, Elisabetta Ada Cavalcanti-Adam: Hyaluronan hydrogels delivering BMP-6 for local targeting of malignant plasma cells and osteogenic differentiation of mesenchymal stromal cells. In: Acta Biomaterialia, 96 (2019). - S. 258-270.
doi:10.1016/j.actbio.2019.07.018

Andrea Palamidessi, Chiara Malinverno, Emanuela Frittoli, Salvatore Corallino, Elisa Barbieri, Sara Sigismund, Galina V. Beznoussenko, Emanuele Martini, Massimiliano Garre, Ines Ferrara, Claudio Tripodo, Flora Ascione, Elisabetta Ada Cavalcanti-Adam, Qingsen Li, Pier Paolo Di Fiore, Dario Parazzoli, Fabio Giavazzi, Roberto Cerbino, Giorgio Scita: Unjamming overcomes kinetic and proliferation arrest in terminally differentiated cells and promotes collective motility of carcinoma. In: Nature Materials, 18 (2019). - S. 1252-1263.
doi:10.1038/s41563-019-0425-1

2018

Marta Fratini, Tina Wiegand, Charlotta Funaya, Zhongxiang Jiang, Pranav N. M. Shah, Joachim P. Spatz, Elisabetta Ada Cavalcanti-Adam, Steeve Boulant: Surface immobilization of viruses and nanoparticles elucidates early events in clathrin-mediated endocytosis. In: ACS Infectious Diseases, 4 (2018). - S. 1585-1600.
doi:10.1021/acsinfecdis.8b00134

Martin Müller, Birgit Urban, Berthold Reis, Xiaoqian Yu, Anna Luise Grab, Elisabetta Ada Cavalcanti-Adam, Dirk Kuckling: Switchable release of bone morphogenetic protein from thermoresponsive poly (NIPAM-co-DMAEMA)/cellulose sulfate particle coatings. In: Polymers, 10 (2018). - .
doi:10.3390/polym10121314

Francesca Posa, Adriana Di Benedetto, Elisabetta Ada Cavalcanti-Adam, Graziana Colaianni, Chiara Porro, Teresa Trotta, Giacomina Brunetti, Lorenzo Lo Muzio, Maria Grano, Giorgio Mori: Vitamin D promotes MSC osteogenic differentiation stimulating cell adhesion and αVβ3 expression. In: Stem Cells International, 2018 (2018). - .
doi:10.1155/2018/6958713

2017

Katrin Talkenberger, Elisabetta Ada Cavalcanti-Adam, Anja Voss-Böhme, Andreas Deutsch: Amoeboid-mesenchymal migration plasticity promotes invasion only in complex heterogeneous microenvironments. In: Scientific Reports, 7 (2017). - .
doi:10.1038/s41598-017-09300-3

Pier Nicola Sergi, Elisabetta Ada Cavalcanti-Adam: Biomaterials and computation : a strategic alliance to investigate emergent responses of neural cells. In: Biomaterials Science, 5 (2017). - S. 648-657.
doi:10.1039/C6BM00871B

Ralf Petzold, D. Vehlow, B. Urban, A. L. Grab, Elisabetta Ada Cavalcanti-Adam, V. Alt, M. Müller: Colloid, adhesive and release properties of nanoparticular ternary complexes between cationic and anionic polysaccharides and basic proteins like bone morphogenetic protein BMP-2. In: Colloids and Surfaces B: Biointerfaces, 151 (2017). - S. 58-67.
doi:10.1016/j.colsurfb.2016.11.029

Tobias G. Kapp, Florian Rechenmacher, Stefanie Neubauer, Oleg V. Maltsev, Elisabetta Ada Cavalcanti-Adam, Revital Zarka, Ute Reuning, Johannes Notni, Hans-Jürgen Wester, Carlos Mas-Moruno, Joachim Spatz, Benjamin Geiger, Horst Kessler: A comprehensive evaluation of the activity and selectivity profile of ligands for RGD-binding integrins. In: Scientific Reports, 7 (2017). - .
doi:10.1038/srep39805

Elisa Migliorini, Patrick Horn, Tamás Haraszti, Seraphine V. Wegner, Christian Hiepen, Petra Knaus, Ralf P. Richter, Elisabetta Ada Cavalcanti-Adam: Enhanced Biological Activity of BMP‐2 Bound to Surface‐Grafted Heparan Sulfate. In: Advanced Biosystems, 1 (2017). - .
doi:10.1002/adbi.201600041

Diego Pallarola, Ilia Platzman, Alexander Bochen, Elisabetta Ada Cavalcanti-Adam, Markus Axmann, Horst Kessler, Benjamin Geiger, Joachim P. Spatz: Focal adhesion stabilization by enhanced integrin-cRGD binding affinity. In: BioNanoMaterials, 18 (2017). - .
doi:10.1515/bnm-2016-0014

Roger Oria, Tina Wiegand, Jorge Escribano, Alberto Elosegui-Artola, Juan Jose Uriarte, Cristian Moreno-Pulido, Ilia Platzman, Pietro Delcanale, Lorenzo Albertazzi, Daniel Navajas, Xavier Trepat, José Manuel García-Aznar, Elisabetta Ada Cavalcanti-Adam, Pere Roca-Cusachs: Force loading explains spatial sensing of ligands by cells. In: Nature, 552 (2017). - S. 219-224.
doi:10.1038/nature24662

Adriana Di Benedetto, Francesca Posa, Claudia Carbone, Stefania Cantore, Giacomina Brunetti, Matteo Centonze, Maria Grano, Lorenzo Lo Muzio, Elisabetta Ada Cavalcanti-Adam, Giorgio Mori: NURR1 downregulation favors osteoblastic differentiation of MSCs. In: Stem Cells International, 2017 (2017). - .
doi:10.1155/2017/7617048

Anja Seckinger, Jose Antonio Delgado, Samuel Moser, Laura Moreno, Brigitte Neuber, Anna Grab, Susanne Lipp, Juana Merino, Felipe Prosper, Martina Emde, Camille Delon, Melanie Latzko, Reto Gianotti, Remo Lüoend, Ramona Murr, Ralf J. Hosse, Lydia Jasmin Harnisch, Marina Bacac, Tanja Fauti, Christian Klein, Aintzane Zabaleta, Jens Hillengass, Elisabetta Ada Cavalcanti-Adam, Anthony D. Ho, Michael Hundemer, Jesus F. San Miguel, Klaus Strein, Pablo Umaña, Dirk Hose, Bruno Paiva, Minh Diem Vu: Target expression, generation, preclinical activity, and pharmacokinetics of the BCMA-T cell bispecific antibody EM801 for multiple myeloma treatment. In: Cancer Cell, 31 (2017). - S. 396-410.
doi:10.1016/j.ccell.2017.02.002

Giorgio Mori, Giacomina Brunetti, Filiberto Mastrangelo, Elisabetta Ada Cavalcanti-Adam: Targeting Adult Mesenchymal Stem Cells Plasticity for Tissue Regeneration. In: Stem Cells International, 2017 (2017). - .
doi:10.1155/2017/4532179

2016

Rebecca Medda, Arnold Giske, Elisabetta Ada Cavalcanti-Adam: Challenges in imaging cell surface receptor clusters. In: Optics and Lasers in Engineering, 76 (2016). - S. 3-8.
doi:10.1016/j.optlaseng.2015.03.020

Viktoria Schaufler, Helmi Czichos-Medda, Vera Hirschfeld-Warnecken, Stefanie Neubauer, Florian Rechenmacher, Rebecca Medda, Horst Kessler, Benjamin Geiger, Joachim P. Spatz, Elisabetta Ada Cavalcanti-Adam: Selective binding and lateral clustering of α5β1 and αvβ3 integrins : Unraveling the spatial requirements for cell spreading and focal adhesion assembly. In: Cell Adhesion & Migration, 10 (2016). - S. 505-515.
doi:10.1080/19336918.2016.1163453

Elisa Migliorini, Anne Valat, Catherine Picart, Elisabetta Ada Cavalcanti-Adam: Tuning cellular responses to BMP-2 with material surfaces. In: Cytokine & Growth Factor Reviews, 27 (2016). - S. 43-54.
doi:10.1016/j.cytogfr.2015.11.008

Francesca Posa, Adriana Di Benedetto, Graziana Colaianni, Elisabetta Ada Cavalcanti-Adam, Giacomina Brunetti, Chiara Porro, Teresa Trotta, Maria Grano, Giorgio Mori: Vitamin D effects on osteoblastic differentiation of mesenchymal stem cells from dental tissues. In: Stem Cells International, 2016 (2016). - .
doi:10.1155/2016/9150819

2015

Katrin Böttger, Haralambos Hatzikirou, Anja Voss-Böhme, Elisabetta Ada Cavalcanti-Adam, Miguel A. Herrero, Andreas Deutsch: An emerging Allee effect is critical for tumor initiation and persistence. In: PLoS Computational Biology, 11 (2015). - .
doi:10.1371/journal.pcbi.1004366

Kristin Hauff, Chiara Zambarda, Miriam Dietrich, Maria Halbig, Anna Luise Grab, Rebecca Medda, Elisabetta Ada Cavalcanti-Adam: Matrix-immobilized BMP-2 on microcontact printed fibronectin as an in vitro tool to study BMP-mediated signaling and cell migration. In: Frontiers in Bioengineering and Biotechnology, 3 (2015). - .
doi:10.3389/fbioe.2015.00062

Elisabeth H. Schwab, Theresa L. M. Pohl, Tamás Haraszti, Gerburg K. Schwaerzer, Christian Hiepen, Joachim P. Spatz, Petra Knaus, Elisabetta Ada Cavalcanti-Adam: Nanoscale control of surface immobilized BMP-2 : toward a quantitative assessment of BMP-mediated signaling events. In: Nano Letters, 15 (2015). - S. 1526-1534.
doi:10.1021/acs.nanolett.5b00315

Adriana Di Benedetto, Giacomina Brunetti, Francesca Posa, Andrea Ballini, Felice Roberto Grassi, Graziana Colaianni, Silvia Colucci, Enzo Rossi, Elisabetta Ada Cavalcanti-Adam, Lorenzo Lo Muzio, Maria Grano, Giorgio Mori: Osteogenic differentiation of mesenchymal stem cells from dental bud : role of integrins and cadherins. In: Stem Cell Research, 15 (2015). - S. 618-628.
doi:10.1016/j.scr.2015.09.011

Elisabetta Ada Cavalcanti-Adam, Joachim P. Spatz: Receptor clustering control and associated force sensing by surface patterning : when force matters. In: Nanomedicine, 10 (2015). - S. 681-684.
doi:10.2217/nnm.14.234

Qiang Wei, Theresa L. M. Pohl, Anja Seckinger, Joachim P. Spatz, Elisabetta Ada Cavalcanti-Adam: Regulation of integrin and growth factor signaling in biomaterials for osteodifferentiation. In: Beilstein Journal of Organic Chemistry, 11 (2015). - S. 773-783.
doi:10.3762/bjoc.11.87

Judith Guasch, Bert Conings, Stefanie Neubauer, Florian Rechenmacher, Karen Ende, Claudio G. Rolli, Christian Kappel, Viktoria Schaufler, Alexandre Micoulet, Horst Kessler, Hans-Gerd Boyen, Elisabetta Ada Cavalcanti-Adam, Joachim P. Spatz: Segregation versus colocalization : orthogonally functionalized binary micropatterned substrates regulate the molecular distribution in focal adhesions. In: Advanced Materials, 27 (2015). - S. 3737-3747.
doi:10.1002/adma.201500900

2014

Silke Corall, Tamas Haraszti, Tanja Bartoschik, Joachim Pius Spatz, Thomas Ludwig, Elisabetta Ada Cavalcanti-Adam: α5β1-integrin and MT1-MMP promote tumor cell migration in 2D but not in 3D fibronectin microenvironments. In: Computational Mechanics, 53 (2014). - S. 499-510.
doi:10.1007/s00466-013-0960-6

Kristina Glenske, Alena-Svenja Wagner, Thomas Hanke, Elisabetta Ada Cavalcanti-Adam, Sascha Heinemann, Christiane Heinemann, Benjamin Kruppke, Stefan Arnhold, Andreas Moritz, Elisabeth H. Schwab, Hartmut Worch, Sabine Wenisch: Bioactivity of xerogels as modulators of osteoclastogenesis mediated by connexin 43. In: Biomaterials, 35 (2014). - S. 1487-1495.
doi:10.1016/j.biomaterials.2013.11.002

Rebecca Medda, Arne Helth, Patrick Herre, Darius Pohl, Bernd Rellinghaus, Nadine Perschmann, Stefanie Neubauer, Horst Kessler, Steffen Oswald, Jürgen Eckert, Joachim P. Spatz, Annett Gebert, Elisabetta Ada Cavalcanti-Adam: Investigation of early cell–surface interactions of human mesenchymal stem cells on nanopatterned β-type titanium–niobium alloy surfaces. In: Interface Focus, 4 (2014). - .
doi:10.1098/rsfs.2013.0046

Yang Liu, Rebecca Medda, Zheng Liu, Kornelia Galior, Kevin Yehl, Joachim P. Spatz, Elisabetta Ada Cavalcanti-Adam, Khalid Salaita: Nanoparticle tension probes patterned at the nanoscale : impact of integrin clustering on force transmission. In: Nano Letters, 14 (2014). - S. 5539-5546.
doi:10.1021/nl501912g

Ilia Platzman, Katarzyna M. Gadomska, Jan-Willi Janiesch, Ilia Louban, Elisabetta Ada Cavalcanti-Adam, Joachim P. Spatz: Soft/elastic nanopatterned biointerfaces in the service of cell biology. In: Matthieu Piel, Manuel Théry (Hrsg.): Micropatterning in cell biology. Part A. - Amsterdam : Adademic Press, 2014. - S. 237-260.
doi:10.1016/B978-0-12-416742-1.00012-3

2013

Christof Christophis, Elisabetta Ada Cavalcanti-Adam, Maximilian Hanke, Kenji Kitamura, Alexei Gruverman, Michael Grunze, Peter A. Dowben, Axel Rosenhahn: Adherent cells avoid polarization gradients on periodically poled LiTaO₃ ferroelectrics. In: Biointerphases, 8 (2013). - .
doi:10.1186/1559-4106-8-27

Theresa L. M. Pohl, Elisabeth H. Schwab, Elisabetta Ada Cavalcanti-Adam: Covalent binding of BMP-2 on surfaces using a self-assembled monolayer approach. In: JoVE, 78 (2013). - .
doi:10.3791/50842

Elisabeth H. Schwab, Maria Halbig, Kristina Glenske, Alena-Svenja Wagner, Sabine Wenisch, Elisabetta Ada Cavalcanti-Adam: Distinct effects of RGD-glycoproteins on integrin-mediated adhesion and osteogenic differentiation of human mesenchymal stem cells. In: International Journal of Medical Sciences, 10 (2013). - S. 1846-1859.
doi:10.7150/ijms.6908

Florian Rechenmacher, Stefanie Neubauer, Julien Polleux, Carlos Mas‐Moruno, Mariarosaria De Simone, Elisabetta Ada Cavalcanti-Adam, Joachim P. Spatz, Reinhard Fässler, Horst Kessler: Functionalizing αvβ3‐or α5β1‐selective integrin antagonists for surface coating : a method to discriminate integrin subtypes in vitro. In: Angewandte Chemie International Edition, 52 (2013). - S. 1572-1575.
doi:10.1002/anie.201206370

Sabri Rahmouni, Aaron Lindner, Florian Rechenmacher, Stefanie Neubauer, Tariq Rashad Ali Sobahi, Horst Kessler, Elisabetta Ada Cavalcanti-Adam, Joachim Pius Spatz: Hydrogel Micropillars with Integrin Selective Peptidomimetic Functionalized Nanopatterned Tops : A New Tool for the Measurement of Cell Traction Forces Transmitted through αᵥβ₃‐or α₅β₁‐Integrins. In: Advanced Materials, 25 (2013). - S. 5869-5874.
doi:10.1002/adma.201301338

Francesco Gentile, Rebecca Medda, Ling Cheng, Edmondo Battista, Pasquale E. Scopelliti, Paolo Milani, Elisabetta Ada Cavalcanti-Adam, Paolo Decuzzi: Selective modulation of cell response on engineered fractal silicon substrates. In: Scientific Reports, 3 (2013). - .
doi:10.1038/srep01461

2012

Sabine Wenisch, Elisabetta Ada Cavalcanti-Adam, Eva Tryankowski, Oksana Raabe, Olaf Kilian, Christian Heiss, Volker Alt, Stefan Arnhold, Reinhard Schnettler: Light-and transmission-electron-microscopic investigations on distribution of CD44, connexin 43 and actin cytoskeleton during the foreign body reaction to a nanoparticular hydroxyapatite in mini-pigs. In: Acta Biomaterialia, 8 (2012). - S. 2807-2814.
doi:10.1016/j.actbio.2012.03.039

Elisabetta Ada Cavalcanti-Adam, Dimitris Missirlis: Nanoscale Control of Cell Behavior on Biointerfaces. In: João F. Mano (Hrsg.): Biomimetic Approaches for Biomaterials Development. - Weinheim : Wiley-VCH, 2012. - S. 213-236.
doi:10.1002/9783527652273.ch9

Theresa L. M. Pohl, Jan H. Boergermann, Gerburg K. Schwaerzer, Petra Knaus, Elisabetta Ada Cavalcanti-Adam: Surface immobilization of bone morphogenetic protein 2 via a self-assembled monolayer formation induces cell differentiation. In: Acta Biomaterialia, 8 (2012). - S. 772-780.
doi:10.1016/j.actbio.2011.10.019

2010

Alex G. F. de Beer, Elisabetta Ada Cavalcanti-Adam, Günter Majer, M. Lopez-García, H. Kessler, Joachim P. Spatz: Force-induced destabilization of focal adhesions at defined integrin spacings on nanostructured surfaces. In: Physical Review E, 81 (2010). - .
doi:10.1103/PhysRevE.81.051914

Daniel Aydin, Ilia Louban, Nadine Perschmann, Jacques Blümmel, Theobald Lohmüller, Elisabetta Ada Cavalcanti-Adam, Tobias L. Haas, Henning Walczak, Horst Kessler, Roberto Fiammengo, Joachim P. Spatz: Polymeric substrates with tunable elasticity and nanoscopically controlled biomolecule presentation. In: Langmuir, 26 (2010). - S. 15472-15480.
doi:10.1021/la103065x

2009

Marco Arnold, Marco Schwieder, Jacques Blümmel, Elisabetta Ada Cavalcanti-Adam, Mónica López-Garcia, Horst Kessler, Benjamin Geiger, Joachim P. Spatz: Cell interactions with hierarchically structured nano-patterned adhesive surfaces. In: Soft Matter, 5 (2009). - S. 72-77.
doi:10.1039/B815634D

2008

Vera C. Hirschfeld-Warneken, Marco Arnold, Elisabetta Ada Cavalcanti-Adam, Mónica López-García, Horst Kessler, Joachim P. Spatz: Cell adhesion and polarisation on molecularly defined spacing gradient surfaces of cyclic RGDfK peptide patches. In: European Journal of Cell Biology, 87 (2008). - S. 743-750.
doi:10.1016/j.ejcb.2008.03.011

Elisabetta Ada Cavalcanti-Adam, Daniel Aydin, Vera Catherine Hirschfeld‐Warneken, Joachim Pius Spatz: Cell adhesion and response to synthetic nanopatterned environments by steering receptor clustering and spatial location. In: HFSP Journal, 2 (2008). - S. 276-285.
doi:10.2976/1.2976662

Marco Arnold, Vera C. Hirschfeld-Warneken, Theobald Lohmüller, Patrick Heil, Jacques Blümmel, Elisabetta Ada Cavalcanti-Adam, Mónica López-García, Paul Walther, Horst Kessler, Benjamin Geiger, Joachim P. Spatz: Induction of cell polarization and migration by a gradient of nanoscale variations in adhesive ligand spacing. In: Nano Letters, 8 (2008). - S. 2063-2069.
doi:10.1021/nl801483w

2007

Elisabetta Ada Cavalcanti-Adam, Tova Volberg, Alexandre Micoulet, Horst Kessler, Benjamin Geiger, Joachim Pius Spatz: Cell spreading and focal adhesion dynamics are regulated by spacing of integrin ligands. In: Biophysical Journal, 92 (2007). - S. 2964-2974.
doi:10.1529/biophysj.106.089730

Philippe P. Girard, Elisabetta Ada Cavalcanti-Adam, Ralf Kemkemer, Joachim P. Spatz: Cellular chemomechanics at interfaces : sensing, integration and response. In: Soft Matter, 3 (2007). - S. 307-326.
doi:10.1039/B614008D

Antonino G. Secchi, V. Grigoriou, Irving M. Shapiro, Elisabetta Ada Cavalcanti-Adam, Russell J. Composto, Paul Ducheyne, Christopher S. Adams: RGDS peptides immobilized on titanium alloy stimulate bone cell attachment, differentiation and confer resistance to apoptosis. In: Journal of Biomedical Materials Research Part A, 83 (2007). - S. 577-584.
doi:10.1002/jbm.a.31007

2006

Elisabetta Ada Cavalcanti-Adam, Alexandre Micoulet, Jacques Blümmel, Jörg Auernheimer, Horst Kessler, Joachim P. Spatz: Lateral spacing of integrin ligands influences cell spreading and focal adhesion assembly. In: European Journal of Cell Biology, 85 (2006). - S. 219-224.
doi:10.1016/j.ejcb.2005.09.011

2005

Vavara Grigoriou, Irving M. Shapiro, Elisabetta Ada Cavalcanti-Adam, Russell J. Composto, Paul Ducheyne, Christopher S. Adams: Apoptosis and survival of osteoblast-like cells are regulated by surface attachment. In: The Journal of Biological Chemistry, 280 (2005). - S. 1733-1739.
doi:10.1074/jbc.M402550200

Elisabetta Ada Cavalcanti-Adam, Pascal Tomakidi, Martin Bezler, Joachim Pius Spatz: Geometric organization of the extracellular matrix in the control of integrin-mediated adhesion and cell function in osteoblasts. In: Progress in Orthodontics, 6 (2005). - S. 232-237.

2004

Marco Arnold, Elisabetta Ada Cavalcanti-Adam, Roman Glass, Jacques Blümmel, Wolfgang Eck, Martin Kantlehner, Horst Kessler, Joachim P. Spatz: Activation of integrin function by nanopatterned adhesive interfaces. In: ChemPhysChem, 5 (2004). - S. 383-388.
doi:10.1002/cphc.200301014

Roman Glass, Marco Arnold, Elisabetta Ada Cavalcanti-Adam, Jacques Blümmel, Christian Haferkemper, Charlotte Dodd, Joachim P. Spatz: Block copolymer micelle nanolithography on non-conductive substrates. In: New Journal of Physics, 6 (2004). - .
doi:10.1088/1367-2630/6/1/101

2002

Elisabetta Ada Cavalcanti-Adam, I. M. Shapiro, R. J. Composto, E. J. Macarak, Christopher S. Adams: RGD peptides immobilized on a mechanically deformable surface promote osteoblast differentiation. In: Journal of Bone and Mineral Research, 17 (2002). - S. 2130-2140.
doi:10.1359/jbmr.2002.17.12.2130

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